<p>Biopolymers synthesized from renewable biomass resources offer a sustainable alternative to conventional plastics, mitigating environmental concerns associated with petroleum-based polymers and addressing plastic waste management issues. The aim of this study is to manufacture bioplastic films using corn and neem starch and characterize it to know the effect of different plasticizers such as glycerol and fructose on its mechanical and hydrophilic characteristics. The characterization was carried out by tensile test using universal testing machine, film thickness using digital micrometer, density using densimeter, morphology using scanning electron microscopy (SEM), Fourier transform infrared spectroscopy (FTIR) using infrared spectrophotometer, moisture content, solubility and absorption in water was done by calculating the change in weight percentage. The results show that the thickness of the plasticized bioplastic films ranged from 0.8 to 1.58&#xa0;mm and the density ranged from 1.39 to 1.50&#xa0;g/cm³. The highest tensile strength of 19.12&#xa0;MPa was noticed for the plasticized bioplastic film with 30 wt% glycerol and fructose plasticizer combination. The SEM and FTIR study revealed the plasticized bioplastic film’s surface morphology and chemical functional groups. In the case of hydrophilic characteristics of the plasticized bioplastic films observations reveal that increasing the plasticizer wt% decreases the hydrophilic characteristics. The observations of the experiment conclude that the plasticized bioplastic film with 30 wt% glycerol and fructose plasticizer combination with thermal stability upto 97&#xa0;°C holds great potential as a biopolymer for packaging applications.</p> Graphical abstract <p></p>