Scholarlink

Background <p>Physical inactivity (PI) is a major contributor to adiposity and cardiometabolic morbidity.</p> Objective <p>To synthesize evidence of the association between PI and childhood overweight/obesity (OV/OB) and metabolically unhealthy obesity (MUO; OB accompanied by cardiometabolic abnormalities) risk.</p> Methods <p>A systematic review and meta-analysis of prospective epidemiological studies and randomized controlled trials (RCTs) was performed following PRISMA guidelines (PROSPERO ID: CRD42023482960). Studies conducted in Western countries with 2-19-year-old participants, PI-related exposures (time/frequency of engagement in various sedentary behaviors) and interventions (targeting PI reduction), OV/OB-/MUO-related outcomes and ≥ 12-month follow-up were extracted from PubMed and Scopus (publication timeframe: 01/01/2013-30/06/2024). Study quality was assessed through risk of bias (RoB).</p> Results <p>Among 86 prospective epidemiological studies with OV/OB-related outcomes (42% high-RoB), PI was evaluated objectively (accelerometry) in 34 and subjectively (questionnaires) in 57 (29% and 68% reported detrimental associations, respectively). In random-effects meta-analysis, subjectively-assessed total screen time was positively associated with body mass index (BMI) [<i>n</i> = 4; beta (95%CI): 0.116 (0.037, 0.195) kg/m<sup>2</sup>] and BMI z-score [<i>n</i> = 8; beta (95%CI): 0.032 (0.002, 0.063)], while television viewing was positively associated with BMI [<i>n</i> = 3; beta (95%CI): 0.227 (0.025, 0.428) kg/m<sup>2</sup>], BMI z-score [<i>n</i> = 4; beta (95%CI): 0.042 (0.007, 0.077)] and OV/OB incidence [<i>n</i> = 5; logRR (95%CI): 0.089 (0.044, 0.133)]. The sole RCT (low-RoB) indicated a beneficial effect of reducing sedentariness on anthropometric indices. Two prospective epidemiological studies (high-RoB) suggested positive associations between subjectively-assessed total screen time and MUO-related outcomes.</p> Conclusions <p>Screen time is positively associated with indicators of childhood OV/OB risk, while limited evidence also supports its detrimental role in MUO.</p>

错误：搜索内容不能为空，请输入英文关键词
错误：关键词超出字数限制，请精简
高级检索

A Systematic Review and Meta-Analysis of Longitudinal Studies Exploring the Link Between Physical Inactivity and Indicators of Childhood Overweight/Obesity and Metabolically Unhealthy Obesity Risk in Western Countries

  • 期刊论文

  • 出版模式：

    开放获取

  • 发表日期：

    2026年1月3日

查看全文
  • Michael Georgoulis,
  • Ismini Grapsa,
  • Giannis Arnaoutis,
  • Alexandra Karachaliou,
  • Demosthenes Panagiotakos,
  • Georgios Saltaouras,
  • Eirini Bathrellou,
  • Mary Yannakoulia,
  • George Dimitrakopoulos,
  • Meropi D. Kontogianni

摘要

Background

Physical inactivity (PI) is a major contributor to adiposity and cardiometabolic morbidity.

Objective

To synthesize evidence of the association between PI and childhood overweight/obesity (OV/OB) and metabolically unhealthy obesity (MUO; OB accompanied by cardiometabolic abnormalities) risk.

Methods

A systematic review and meta-analysis of prospective epidemiological studies and randomized controlled trials (RCTs) was performed following PRISMA guidelines (PROSPERO ID: CRD42023482960). Studies conducted in Western countries with 2-19-year-old participants, PI-related exposures (time/frequency of engagement in various sedentary behaviors) and interventions (targeting PI reduction), OV/OB-/MUO-related outcomes and ≥ 12-month follow-up were extracted from PubMed and Scopus (publication timeframe: 01/01/2013-30/06/2024). Study quality was assessed through risk of bias (RoB).

Results

Among 86 prospective epidemiological studies with OV/OB-related outcomes (42% high-RoB), PI was evaluated objectively (accelerometry) in 34 and subjectively (questionnaires) in 57 (29% and 68% reported detrimental associations, respectively). In random-effects meta-analysis, subjectively-assessed total screen time was positively associated with body mass index (BMI) [n = 4; beta (95%CI): 0.116 (0.037, 0.195) kg/m2] and BMI z-score [n = 8; beta (95%CI): 0.032 (0.002, 0.063)], while television viewing was positively associated with BMI [n = 3; beta (95%CI): 0.227 (0.025, 0.428) kg/m2], BMI z-score [n = 4; beta (95%CI): 0.042 (0.007, 0.077)] and OV/OB incidence [n = 5; logRR (95%CI): 0.089 (0.044, 0.133)]. The sole RCT (low-RoB) indicated a beneficial effect of reducing sedentariness on anthropometric indices. Two prospective epidemiological studies (high-RoB) suggested positive associations between subjectively-assessed total screen time and MUO-related outcomes.

Conclusions

Screen time is positively associated with indicators of childhood OV/OB risk, while limited evidence also supports its detrimental role in MUO.