Advancements in Comorbidity Screening and Multidisciplinary Symptom Management for Hidradenitis Suppurativa

Understanding comorbidities associated with Hidradenitis Suppurativa (HS) is essential given their significant impact on overall health. This review employs an organ system-based framework to categorize comorbidities associated with HS, and highlights screening and multidisciplinary management based on recent data.

Historically, many studies have demonstrated an increased prevalence of metabolic syndrome, inflammatory bowel disease, and mood disorders among patients with HS. More recent studies have also reported associations with asthma, chronic kidney disease, thyroid disease and sexual dysfunction. Moreover, novel treatment options for HS comorbid diseases, including diabetes and obesity, have shown promising results in the management of HS. This further supports the multisystemic implications of HS.

HS and its comorbidities place a substantial burden on the healthcare system and often result in high morbidity and mortality. Dermatologists should be aware of comorbidities associated with HS and collaborate with physicians in other specialties for multidisciplinary management.