Weight Loss, Sarcopenic Obesity, and Mobility in Older Adults: Clinical and Rehabilitation Perspectives
摘要
Sarcopenic obesity represents the coexistence of excess adiposity and impaired muscle function, contributing to disability and loss of independence. This review examines how intentional weight loss treatments interact with muscle capacity and mobility outcomes in this population, with a focus on rehabilitation and exercise-based strategies.
Recent FindingsWeight loss improves cardiometabolic health and reduces mechanical load but may accelerate declines in lean mass and strength if not paired with resistance training. Multicomponent exercise interventions combining resistance, aerobic, and balance training provide benefits for preserving muscle function and improving physical function. Data on pharmacologic weight-loss therapies remain limited with respect to muscle and mobility outcomes.
SummaryWeight loss in adults with sarcopenic obesity is a clinical double-edged sword. Mobility-centered, exercise-based interventions are essential to preserve muscle capacity during adiposity reduction. Future research should prioritize functionally meaningful outcomes and standardized rehabilitation frameworks to optimize mobility and independence.