Purpose of Review <p>Home-Based Primary Care (HBPC) supports over 2 million homebound Americans aged 65 and older, addressing barriers to traditional care. This review examines its benefits in providing comprehensive, patient-centered care to frail and vulnerable individuals while addressing their physical, social, and mental health needs.</p> Recent Findings <p>HBPC has gained renewed attention due to rising chronic disease prevalence, supportive policies, and value-based care models. It benefits patients with chronic conditions, severe mobility challenges, and those requiring end-of-life care. Multidisciplinary teams address social determinants of health, including food access, transportation, and home safety. Innovations like virtual behavioral health services and remote monitoring enhance care delivery. Advance care planning and frailty management improve quality of life and reduce hospitalizations.</p> Summary <p>HBPC delivers holistic care for homebound individuals through interdisciplinary, patient-focused approaches. By integrating technology and behavioral health, it addresses complex needs, improves outcomes, and expands access to care for vulnerable populations.</p>