Prehabilitation within Enhanced Recovery After Surgery Protocols in Gynecologic Oncology: Current Evidence and Future Directions
摘要
To synthesize current evidence on the role of prehabilitation within Enhanced Recovery After Surgery pathways in gynecologic oncology, clarify which patients benefit most, and outline pragmatic elements that can be implemented before cancer surgery.
Recent findingsMultimodal prehabilitation programs that combine targeted exercise, nutrition optimization, and psychological support appear feasible in gynecologic oncology and are associated with earlier mobilization, faster return of bowel function, earlier oral intake, and shorter length of stay when integrated into ERAS, without increased complications. Small randomized and prospective studies suggest improvements in functional capacity and patient reported outcomes, but heterogeneity in patient selection, program content, and adherence limits certainty and comparability across trials. Evidence is converging that risk stratification and individualized program tailoring improve uptake and clinical relevance.
SummaryPrehabilitation is a plausible and increasingly supported adjunct to ERAS for gynecologic cancer surgery, with signals of benefit on early recovery and patient experience. Priority research needs include multicenter randomized trials focused on high-risk cohorts, standardized core components and outcome sets, and implementation studies that integrate prehabilitation into routine preoperative pathways and adjuvant treatment timelines