Purpose of Review <p>Cognitive behavioral therapy (CBT) is a widely recommended intervention for the treatment of menopause symptoms, particularly when hormonal treatment is not advised or is not preferred. This review describes how CBT has been used to treat vasomotor symptoms, sleep difficulties, mood and anxiety symptoms, cognitive concerns, and sexual dysfunction, noting key literature from the growing research base. Strengths and needs of research in and implementation of CBT and mindfulness-based interventions (MBIs) for menopause symptoms are highlighted.</p> Recent Findings <p>In the past decade, MBIs have been included in the repertoire of CBT skills and interventions and are gaining an evidence base for addressing menopause symptoms. Recent studies on CBT and MBIs for menopause symptoms illustrate how they can impact menopause symptoms, including sexual difficulties, cognitive concerns, and unhelpful beliefs towards aging and one’s body. Findings also suggest that these interventions can be delivered in multiple ways, including virtually. The article also identifies the applicability of CBT and MBIs to areas of concern and importance for women in the menopause transition but that need more attention and study. These include consideration of cultural context, workplace environment, psychosocial stressors, body image, irritability, and women living with mental health histories.</p> Summary <p>CBT and MBIs offer effective nonhormonal, nonpharmacological ways of helping women manage difficult and interfering menopause symptoms. They also hold promise in helping women address multiple concerns during the menopause transition and in positioning women with skills for continued healthy aging.</p>