<p>The main objective of this panoramic review is to examine the herbal medicinal plants that are utilized as anti-fertility activities all over the globe. Traditionally, the herbs were the only source for people to treat any disease, and afterward, as much of the modern method and treatment are introduced, but it cannot replace the requirement of herbal treatment for various diseases. There are various such diseases that are not treated by allopathic medicine but treated by herbal medicine. Many of the modern methods are frequently used as males and females for contraception, which are discussed in this review below, but these methods cause various types of side effects, which are very few or neglected in using medicinal plant-derived products. Herbal contraceptives are the efficient treatment for the exhibition of natural, free toxicity, 100% anti-fertility activity, including anti-implantation, anti-ovulatory, anti-spermatogenic, abortifacient, and estrogenic activities in males and females. People, including both males and females, who are desired for contraception without any side effects prefer herbal methods. Although herbal contraceptive regularity in the time interval of doses. Therefore, this review provides the information according to various recent research conducted using PRISMA for the herbal medicine being used as a potent anti-fertility agent.</p> Graphical abstract <p></p>