Effect of acupressure on migraine: a systematic review and meta-analysis

Migraine, a prevalent neurological disorder, affects about 14.4% of the global population, ranking among the leading causes of disability, especially in young women. Acupressure, a non-invasive therapy akin to acupuncture, has emerged as a potential intervention for migraine management. However, its effectiveness remains inconclusive due to the lack of comprehensive systematic reviews. This study aims to systematic review and meta-analysis existing literature to investigate the effect of acupressure on migraine symptoms. Methods Adhering to PRISMA guidelines, a comprehensive search strategy was employed across multiple databases. Eligible studies included randomized controlled trials (RCTs), cohort studies and case reports involving individuals diagnosed with various migraine types. Data synthesis and analysis were conducted using STATA 14, with meta-analyses performed on available quantitative data. Results From 250 initial records, 12 studies were included, comprising ten RCTs, one cohort study, and one case report, with six RCTs included in the meta-analysis. Results showed mixed findings regarding acupressure’s impact on migraine symptoms, with improvements noted in headache intensity, frequency, duration, and nausea. However, substantial heterogeneity among studies and methodological limitations were identified, limiting the conclusiveness of the evidence. Conclusion Despite promising results, this review underscores the need for further research. Methodologically robust studies with larger sample sizes are warranted to elucidate acupressure’s role in migraine treatment. Nonetheless, continued investigation into complementary therapies like acupressure holds promise for providing non-invasive options for migraine management.