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The origin of ovarian Leydig cells: a possibly solved enigma?

  • José-Luis Carrasco-Juan,
  • Miriam González-Gómez,
  • Olga Tapia,
  • Sonia García-Hernández,
  • Abian Vega-Falcón,
  • Rafael Méndez-Medina,
  • Hugo Álvarez-Argüelles Cabrera,
  • Lucio Díaz-Flores

摘要

Over the years, the origin of ovarian Leydig cells has been, and still is, a topic subject to deep debate. Seven years ago, we proposed that this origin resided in intraneural elements that came from a possible reservoir of neural crest cells, a reservoir that may be located in the ganglia of the celiac plexus. We believe we have found the evidence necessary to prove this hypothesis.