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<p>Atopic dermatitis (AD) is a chronic inflammatory skin disorder with rising prevalence worldwide. Its pathogenesis involves a complex interplay between genetic predisposition, skin barrier dysfunction, and immune dysregulation. Environmental exposures, including allergens and pollutants, are well-recognized triggers of disease activity. Increasing attention is now being directed toward the role of climate, which may critically modulate AD onset and severity. This review examines climate-related stressors and their impact on AD, with a particular focus on extreme weather events, and outlines strategies for personalized management tailored to local climatic conditions.</p>

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Atopic Dermatitis and Climate: Environmental Stressors and Care Strategies

  • 期刊论文

  • 出版模式：

    开放获取

  • 发表日期：

    2025年10月7日

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  • Filomena Russo,
  • Alexander Zink,
  • Nina Magnolo,
  • Enrico Scala,
  • Emanuele Scala

摘要

Atopic dermatitis (AD) is a chronic inflammatory skin disorder with rising prevalence worldwide. Its pathogenesis involves a complex interplay between genetic predisposition, skin barrier dysfunction, and immune dysregulation. Environmental exposures, including allergens and pollutants, are well-recognized triggers of disease activity. Increasing attention is now being directed toward the role of climate, which may critically modulate AD onset and severity. This review examines climate-related stressors and their impact on AD, with a particular focus on extreme weather events, and outlines strategies for personalized management tailored to local climatic conditions.