A pan-India KAP survey: insights from diabetologists, endocrinologists, and consulting physicians on diabetes pruritus
摘要
Diabetes mellitus (DM) often leads to complications such as pruritus, significantly impacting patients’ quality of life (QoL). Objective This survey aimed to gather insights from healthcare professionals (HCPs) on the prevalence, diagnosis, and management of diabetic pruritus.
MethodsA quantitative cross-sectional survey was conducted by the Research Society for the Study of Diabetes in India, involving 4173 HCPs, including diabetologists, endocrinologists, and consulting physicians. The survey collected data on diabetic pruritus prevalence, diagnosis latency, HbA1c correlations, associated drug classes, and pruritus’s impact on QoL and clinical practices.
ResultsThe survey found that 37.7% of HCPs encountered pruritus in 10–20% of diabetic cases, with 13.4% seeing it in over 30%. Pruritus onset typically occurred 6–15 years post-diagnosis, significantly impacting QoL: 26.4% of patients had impaired sleep, 25.7% reported mood disturbances, and 24.1% suffered from social anxiety. Elevated HbA1c levels, particularly in the 8–10% and 10–12% ranges, were frequently associated with pruritus. Common complications included xerosis, fungal infections, and drug-related pruritus linked to metformin and combination therapies. Preferred treatments included topical treatments like calamine lotion and 1% pramoxine hydrochloride and systemic treatments like first-generation antihistamines like hydroxyzine.
ConclusionThis study underscores the increasing prevalence of diabetic pruritus in HCPs’ daily practices, often linked to poor glycemic control and certain medications. Despite its significant impact on QoL, awareness remains low. Better diagnostic and management strategies with improved patient education are essential to enhance care and outcomes.