The effect of high-concentration CO2-enriched water on sensory neuropathy in patients with diabetes referred to an endocrine clinic

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发表日期：

2024年9月16日

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Saeid Kalbasi,
Azam Erfanifar,
Sasan Shafiei,
Seyed Sajad Hosseini,
Latif Gachkar,
Maryam Golmoohammadi,
Amin Zaki Zadeh,
Safoura Alsadat Hoseini

摘要

Objective

This study aimed to assess the possible therapeutic effects of CO2-enriched water on the sensory complications of diabetic neuropathy.

Methods

Fifty-eight patients entered the study, each participant received highly concentrated CO2-enriched water once a day for 15 days and then once a week for 3 months. The prevalence of neuropathy-related signs and symptoms was assessed using standard questionnaires and clinical tests.

Results

In all patients, significant reductions were observed in numbness, pain, cramp, fatigue, and other indexes and sensory and functionality tests of feet (p < 0.001).

Conclusion

Immersion of neuropathic limp in CO2-enriched water for 15 days and 3 months improved patients’ symptoms. These improvements occur rapidly at first but slow down over time. Accordingly, CO2 therapy can be used to improve the sensory function of limbs in patients with diabetes.