Global research trends on diabetic islet regeneration (2012–2022): a ten-year bibliometric study

Diabetes mellitus (DM), a prevalent chronic metabolic disorder, has seen an escalating incidence each year, thereby imposing significant burdens on both public health and socio-economic structures. Although numerous outstanding studies have focused on the regeneration of diabetic islets, a gap exists in the form of comprehensive bibliometric analyses in this area.

We employed bibliometric methods to encapsulate and depict the worldwide research directions in this field. Our study engaged in a detailed screening of 552 scholarly articles on diabetic islet regeneration from 2012 to 2022.

Our findings indicate a consistent upward trajectory in both publications and citations. Geographically, China holds the forefront in terms of publication volume, followed closely by the United States, India, and Japan. However, in citation quantity, the United States takes the lead, with China, India, and Italy trailing. Institutional contributions are led by the University of Pennsylvania in publication volume, while Harvard University ranks first in citation frequency. Notably, the Journal of Ethnopharmacology emerged as the most prolific journal and achieved a high citation ranking. The current research focal points encompass cell maturation, regenerative medicine, cellular replacement, and gene expression analysis.

This study offers an exhaustive bibliometric perspective on the global research trends concerning diabetic islet regeneration over the last decade. It highlights that areas such as beta-cell proliferation, regeneration, and replacement continue to be pivotal in the research landscape for diabetes management.