<p>Lime peels, often discarded as waste in the food and beverages industry, encompass a vast range of indispensable bioactive compounds showing various therapeutic properties (e.g., antioxidant, bacteriostatic, antifungal, cytotoxic activities, etc.). This study aimed to optimize the drying conditions of <i>Citrus aurantifolia</i> peels dried using traditional (sun drying) and alternative drying methods (tray drying and vacuum drying), extract essential oil using hydro-distillation, and enhance its stability through nano-encapsulation with polyethylene glycol (PEG) 4000. Tray drying at 50&#xa0;°C preserved the highest levels of phenolics (73.41 ± 0.15&#xa0;mg GAE/g), flavonoids (45.52 ± 0.21&#xa0;mg QE/g), radical activity (84.91 ± 0.09%), and ascorbic acid (136.54 ± 0.27&#xa0;mg/100&#xa0;g). Hydro-distillation yielded 1.3% (v/v) essential oil, which was characterized using NMR and FTIR analysis. Nano-encapsulation achieved an encapsulation efficiency of 51.1 ± 1.19%, improving stability, bioactivity, and showed antimicrobial activity against pathogenic microbes. These findings support the sustainable utilization of lime peel waste in food and pharmaceutical applications.</p>

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Nano-encapsulation and characterization of essential oil from dried Citrus aurantifolia peel: antioxidant, functional and antimicrobial potential

  • Devika Manoj Kumar,
  • Abhishek Dutt Tripathi,
  • Alisha Nandan,
  • Arunima Tripathi,
  • Aparna Agarwal,
  • Deepak Kumar,
  • Ankita Hooda,
  • Javed Masood Khan

摘要

Lime peels, often discarded as waste in the food and beverages industry, encompass a vast range of indispensable bioactive compounds showing various therapeutic properties (e.g., antioxidant, bacteriostatic, antifungal, cytotoxic activities, etc.). This study aimed to optimize the drying conditions of Citrus aurantifolia peels dried using traditional (sun drying) and alternative drying methods (tray drying and vacuum drying), extract essential oil using hydro-distillation, and enhance its stability through nano-encapsulation with polyethylene glycol (PEG) 4000. Tray drying at 50 °C preserved the highest levels of phenolics (73.41 ± 0.15 mg GAE/g), flavonoids (45.52 ± 0.21 mg QE/g), radical activity (84.91 ± 0.09%), and ascorbic acid (136.54 ± 0.27 mg/100 g). Hydro-distillation yielded 1.3% (v/v) essential oil, which was characterized using NMR and FTIR analysis. Nano-encapsulation achieved an encapsulation efficiency of 51.1 ± 1.19%, improving stability, bioactivity, and showed antimicrobial activity against pathogenic microbes. These findings support the sustainable utilization of lime peel waste in food and pharmaceutical applications.