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<p>The persistent shortage of organs, cadavers, and research participants in medicine has prompted proposals such as human 'bodyoids'—engineered human bodies lacking neural components necessary for consciousness and pain. Here, we critically assess the feasibility and ethics of creating bodyoids, highlighting significant technological challenges that render their development highly speculative and economically impractical. We further argue that even if feasible, engineering bodies devoid of consciousness raises profound ethical issues, including moral ambiguity, potential dehumanization, and legal concerns akin to those surrounding patients with severe brain injuries. Our analysis suggests that pursuing bodyoids raises concerns about respect for human life and dignity. We conclude that resources should instead focus on more viable and ethically sound alternatives to address urgent clinical needs in transplantation and research.</p>

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No Brain, No Pain, No Problem? The Case Against Creating Human ‘Bodyoids’

  • 期刊论文

  • 发表日期：

    2025年11月11日

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  • Daniel Rodger,
  • Daniel J. Hurst,
  • Bruce Blackshaw,
  • Christopher A. Bobier

摘要

The persistent shortage of organs, cadavers, and research participants in medicine has prompted proposals such as human 'bodyoids'—engineered human bodies lacking neural components necessary for consciousness and pain. Here, we critically assess the feasibility and ethics of creating bodyoids, highlighting significant technological challenges that render their development highly speculative and economically impractical. We further argue that even if feasible, engineering bodies devoid of consciousness raises profound ethical issues, including moral ambiguity, potential dehumanization, and legal concerns akin to those surrounding patients with severe brain injuries. Our analysis suggests that pursuing bodyoids raises concerns about respect for human life and dignity. We conclude that resources should instead focus on more viable and ethically sound alternatives to address urgent clinical needs in transplantation and research.