<p>In channel reservoirs, a quantitative characterization of landslide-generated impulse wave-structure interactions is essential for evaluating potential damage to infrastructure and dams. In this study, the problem of landslide-generated impulse waves that attack a vertical wall was investigated in a wave channel via a smooth particle hydrodynamics (SPH) method coupled with a Chrono model. The results indicated that the longitudinal velocity beneath the leading wave crest of an incident impulse wave deviated significantly from solitary wave theory. Moreover, the variation rate in the vertical velocity along the water column coincided with the theoretical prediction only for small wave amplitudes. Nevertheless, the maximum run-up height of an impulse wave can be accurately predicted via the solitary wave theory. Moreover, the maximum wall force during impulse wave-wall interaction was significantly larger than that during solitary wave reflection, particularly for high incident wave amplitudes. Overall, the present study demonstrated some striking differences in the interactions of landslide-generated impulse waves and solitary waves with a vertical wall.</p>