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Objective <p>To determine the in-hospital neonatal outcomes of very preterm and very low birth weight (VLBW) neonates delivered in tertiary neonatal centres in India.</p> Methods <p>This retrospective study analyzed the in-hospital outcomes of very preterm (24<sup>0/7</sup>–31<sup>6/7</sup>) and VLBW (501–1500&#xa0;g) born between January 2018 and December 2022 from 14 tertiary neonatal units across India. Survival during hospital stay and morbidities, including bronchopulmonary dysplasia (BPD) at 36&#xa0;weeks post-menstrual age, intraventricular hemorrhage (IVH), periventricular leukomalacia (PVL), and retinopathy of prematurity (ROP), were analyzed.</p> Results <p>A total of 1691 very preterm neonates with a mean (SD) gestational age of 29 (1.9) weeks were included. Survival on discharge rates were 8.7% at 24&#xa0;weeks, 51% at 25&#xa0;weeks, 67.2% at 26&#xa0;weeks, 86.3% at 27&#xa0;weeks, 89.8% at 28&#xa0;weeks, 92.2% at 29&#xa0;weeks, 93.5% at 30&#xa0;weeks, 97.7% at 31&#xa0;weeks. 87.8% very preterm neonates were alive on discharge; corresponding figures for extreme preterm and extremely low birth weight (ELBW) neonates were 64.4% and 66.3%, respectively. Morbidity rates were 4% (n = 67) for BPD, 2.4% (n = 40) for IVH grade 3 or more, 0.9% (n = 15) for cystic PVL, and 5.1% (n = 86) for ROP requiring treatment. The VLBW group included 1,754 neonates with a mean (SD) gestational age of 29.8 (2.8) weeks. Survival before discharge in the VLBW group was 88%.</p> Conclusion <p>The survival and outcomes of very preterm and VLBW neonates from these tertiary neonatal centers in India were good.</p>

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In-Hospital Outcomes of Very Preterm and Very Low Birth Weight Neonates: A Multicenter Retrospective Study from India

  • 期刊论文

  • 发表日期：

    2026年2月23日

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  • Venkateshwarlu Vardhelli,
  • Praveen Rao Vadije,
  • Rajagopal Kishore Kumar,
  • Vidheya Venkatesh,
  • Arvind Balakrishna Kasaragod

摘要

Objective

To determine the in-hospital neonatal outcomes of very preterm and very low birth weight (VLBW) neonates delivered in tertiary neonatal centres in India.

Methods

This retrospective study analyzed the in-hospital outcomes of very preterm (240/7–316/7) and VLBW (501–1500 g) born between January 2018 and December 2022 from 14 tertiary neonatal units across India. Survival during hospital stay and morbidities, including bronchopulmonary dysplasia (BPD) at 36 weeks post-menstrual age, intraventricular hemorrhage (IVH), periventricular leukomalacia (PVL), and retinopathy of prematurity (ROP), were analyzed.

Results

A total of 1691 very preterm neonates with a mean (SD) gestational age of 29 (1.9) weeks were included. Survival on discharge rates were 8.7% at 24 weeks, 51% at 25 weeks, 67.2% at 26 weeks, 86.3% at 27 weeks, 89.8% at 28 weeks, 92.2% at 29 weeks, 93.5% at 30 weeks, 97.7% at 31 weeks. 87.8% very preterm neonates were alive on discharge; corresponding figures for extreme preterm and extremely low birth weight (ELBW) neonates were 64.4% and 66.3%, respectively. Morbidity rates were 4% (n = 67) for BPD, 2.4% (n = 40) for IVH grade 3 or more, 0.9% (n = 15) for cystic PVL, and 5.1% (n = 86) for ROP requiring treatment. The VLBW group included 1,754 neonates with a mean (SD) gestational age of 29.8 (2.8) weeks. Survival before discharge in the VLBW group was 88%.

Conclusion

The survival and outcomes of very preterm and VLBW neonates from these tertiary neonatal centers in India were good.