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<p>This study assessed a high-resolution ionisation chamber-based PTW 1600SRS detector array (array) for beam profile analysis and patient-specific quality assurance (PSQA) in CyberKnife (CK) stereotactic radiosurgery (SRS) and stereotactic body radiotherapy (SBRT). The goal was to determine its suitability for small fields and non-isocentric delivery, which is unique to robotic platforms. Detector performance was examined for dose linearity, reproducibility, beam profiles, output factors, dose-rate dependence, and verification of the Iris collimator field size. Results were benchmarked against diode-based commissioning data. Clinical applicability was tested by retrospectively verifying 20 intracranial SRS and 20 extracranial SBRT plans using gamma analysis with criteria ranging from 3%/3&#xa0;mm to 1%/1&#xa0;mm, as well as 4%/1&#xa0;mm. The detector showed strong dose linearity (R<sup>2</sup> = 0.999) and stable reproducibility. Beam profiles matched commissioning values within 0.5&#xa0;mm, and output factors agreed within 2% for most collimators, with a maximum deviation of 3% at 5&#xa0;mm. Dose-rate variation remained within 2.5% across relevant SADs. Iris collimator field sizes were consistent with reference measurements. Clinical validation achieved high passing rates, all with tolerance limit of &gt; 95%. It enables accurate beam characterization and reliable PSQA in CK treatments. This work provides the first combined evaluation of beam analysis and clinical validation for this detector on a robotic radiosurgery system, supporting its routine use in small-field quality assurance.</p>

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Bridging precision and practice: dual validation of a high-resolution detector array for beam profiling and patient QA in robotic radiosurgery

  • 期刊论文

  • 发表日期：

    2026年2月24日

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  • Sandeep Singh,
  • Supratik Sen,
  • Abhay Kumar Singh,
  • Dipesh,
  • Manindra Bhushan,
  • Benoy Kumar Singh,
  • Sarthak Tandon,
  • Munish Gairola

摘要

This study assessed a high-resolution ionisation chamber-based PTW 1600SRS detector array (array) for beam profile analysis and patient-specific quality assurance (PSQA) in CyberKnife (CK) stereotactic radiosurgery (SRS) and stereotactic body radiotherapy (SBRT). The goal was to determine its suitability for small fields and non-isocentric delivery, which is unique to robotic platforms. Detector performance was examined for dose linearity, reproducibility, beam profiles, output factors, dose-rate dependence, and verification of the Iris collimator field size. Results were benchmarked against diode-based commissioning data. Clinical applicability was tested by retrospectively verifying 20 intracranial SRS and 20 extracranial SBRT plans using gamma analysis with criteria ranging from 3%/3 mm to 1%/1 mm, as well as 4%/1 mm. The detector showed strong dose linearity (R2 = 0.999) and stable reproducibility. Beam profiles matched commissioning values within 0.5 mm, and output factors agreed within 2% for most collimators, with a maximum deviation of 3% at 5 mm. Dose-rate variation remained within 2.5% across relevant SADs. Iris collimator field sizes were consistent with reference measurements. Clinical validation achieved high passing rates, all with tolerance limit of > 95%. It enables accurate beam characterization and reliable PSQA in CK treatments. This work provides the first combined evaluation of beam analysis and clinical validation for this detector on a robotic radiosurgery system, supporting its routine use in small-field quality assurance.