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<p>This study evaluates the dosimetric accuracy of PLA and ABS 3D-printed phantoms compared to real tissues using Monte Carlo simulations in radionuclide therapy. Materials and methods: A phantom representing average liver and lung volumes, with a 10&#xa0;mm tumor mimic in the liver, was simulated for radioembolization using 1 mCi Tc-99&#xa0;m and 1 mCi Y-90. The dose distribution (DD) was compared across PLA, ABS, and real organ densities. Results: For Tc-99&#xa0;m, PLA showed a + 5.6% DD difference in the liver, and ABS showed − 35.3% and − 40.9% differences in the lungs. For Y-90, PLA had a + 1.7% DD difference in the liver, while ABS showed − 34.2% and − 34.9% differences in the lungs. Conclusion: In MC simulation, PLA is suitable for representing high-density tissues, while ABS is appropriate for simulating moderately low-density tissues.</p>

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Investigation of the tissue equivalence of typical 3D-printing materials for application in internal dosimetry using monte carlo simulations

  • 期刊论文

  • 出版模式：

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  • 发表日期：

    2025年3月13日

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  • Ayse Karadeniz-Yildirim,
  • Handan Tanyildizi-Kokkulunk

摘要

This study evaluates the dosimetric accuracy of PLA and ABS 3D-printed phantoms compared to real tissues using Monte Carlo simulations in radionuclide therapy. Materials and methods: A phantom representing average liver and lung volumes, with a 10 mm tumor mimic in the liver, was simulated for radioembolization using 1 mCi Tc-99 m and 1 mCi Y-90. The dose distribution (DD) was compared across PLA, ABS, and real organ densities. Results: For Tc-99 m, PLA showed a + 5.6% DD difference in the liver, and ABS showed − 35.3% and − 40.9% differences in the lungs. For Y-90, PLA had a + 1.7% DD difference in the liver, while ABS showed − 34.2% and − 34.9% differences in the lungs. Conclusion: In MC simulation, PLA is suitable for representing high-density tissues, while ABS is appropriate for simulating moderately low-density tissues.