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Introduction <p>Pregnancy-related acute kidney injury (PRAKI) remains an important cause of maternal and fetal morbidity and mortality in developing countries. This study evaluated the clinical profile, risk factors, and outcomes of PRAKI in a tertiary care hospital.</p> Materials and Methods <p>This prospective observational study was conducted at LLRM Medical College, Meerut. Pregnant women and postpartum women within six weeks of delivery diagnosed with PRAKI according to KDIGO criteria were included. Clinical, laboratory, and outcome data were collected and analyzed.</p> Results <p>A total of 170 women with PRAKI were studied. The mean age was 27.70 ± 2.64&#xa0;years. Most participants were from rural areas (74.47%), belonged to the upper-lower socioeconomic class (63.53%), and had fewer than four antenatal visits (73.53%). PRAKI occurred most commonly during the third trimester (50%). Anemia with hypertensive disorders was the most frequent pre-morbid condition (27.06%), while oliguria with edema and hypertension was the commonest clinical presentation (27.65%). Preeclampsia/eclampsia (46.47%) and sepsis (30.00%) were the leading causes. According to KDIGO staging, 40.00% patients had Stage 1 disease. Full recovery after ICU admission occurred in 31.18% of cases, whereas 20.00% recovered without ICU admission or dialysis. Preterm low-birth-weight delivery (31.18%) and stillbirth (16.47%) were the major adverse fetal outcomes.</p> Conclusion <p>PRAKI remains a significant obstetric complication. Early antenatal surveillance, timely recognition of risk factors, and prompt management may improve maternal and fetal outcomes.</p>

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Assessment of Prevalence and Clinical Profile and Risk Factors for Pregnancy-Related Acute Kidney Injury in a Tertiary Care Hospital in India

  • 期刊论文

  • 发表日期：

    2026年7月29日

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  • Monika Kashyap,
  • N. Sushma Kumari,
  • Aruna Verma,
  • Yogita Singh,
  • Deepti Pathak

摘要

Introduction

Pregnancy-related acute kidney injury (PRAKI) remains an important cause of maternal and fetal morbidity and mortality in developing countries. This study evaluated the clinical profile, risk factors, and outcomes of PRAKI in a tertiary care hospital.

Materials and Methods

This prospective observational study was conducted at LLRM Medical College, Meerut. Pregnant women and postpartum women within six weeks of delivery diagnosed with PRAKI according to KDIGO criteria were included. Clinical, laboratory, and outcome data were collected and analyzed.

Results

A total of 170 women with PRAKI were studied. The mean age was 27.70 ± 2.64 years. Most participants were from rural areas (74.47%), belonged to the upper-lower socioeconomic class (63.53%), and had fewer than four antenatal visits (73.53%). PRAKI occurred most commonly during the third trimester (50%). Anemia with hypertensive disorders was the most frequent pre-morbid condition (27.06%), while oliguria with edema and hypertension was the commonest clinical presentation (27.65%). Preeclampsia/eclampsia (46.47%) and sepsis (30.00%) were the leading causes. According to KDIGO staging, 40.00% patients had Stage 1 disease. Full recovery after ICU admission occurred in 31.18% of cases, whereas 20.00% recovered without ICU admission or dialysis. Preterm low-birth-weight delivery (31.18%) and stillbirth (16.47%) were the major adverse fetal outcomes.

Conclusion

PRAKI remains a significant obstetric complication. Early antenatal surveillance, timely recognition of risk factors, and prompt management may improve maternal and fetal outcomes.