Scholarlink

<p>Copper hydroxide nanorods (Cu(OH)₂ NRs) were successfully produced using ethanolic leaf extracts of <i>Solanum pubescens</i> utilizing a green synthesis technique. UV–Vis, FTIR, XRD, and SEM–EDX analysis revealed the development of orthorhombic, rod-shaped nanoparticles with an average size of ~ 50&#xa0;nm. Cu(OH)₂ NRs showed significant antibacterial activity, with inhibition zones ranging from 8.55 ± 0.59&#xa0;mm to 9.80 ± 0.68&#xa0;mm against bacterial strains like S. aureus and K. pneumoniae, and 6.20 ± 0.43&#xa0;mm to 7.90 ± 0.55&#xa0;mm against fungal strains like C. albicans. The DPPH experiment demonstrated dose-dependent antioxidant activity, reaching 87.12 ± 5.87% at 80&#xa0;µg/ml and an IC₅₀ value of 51.53&#xa0;µg/ml. Cu(OH)₂ NRs caused up to 42.2% cell death in anticancer experiments against MCF-7 breast cancer cells at the highest dose tested (500&#xa0;µg/mL). The synthesized Cu(OH)₂ nanorods exhibited strong antimicrobial activity, comparable to conventional antibiotics and significantly superior to the plant extract. Their broad-spectrum efficacy, eco-friendly synthesis, and effectiveness against resistant strains highlight their potential as alternative antimicrobial agents.</p>

错误：搜索内容不能为空，请输入英文关键词
错误：关键词超出字数限制，请精简
高级检索

Green synthesis of copper hydroxide nanorods using Solanum pubescens leaf extracts: a promising approach for antimicrobial, antioxidant, and anticancer applications

  • 期刊论文

  • 发表日期：

    2025年8月4日

查看全文
  • C. Neela Mohan,
  • V. Ayyadurai,
  • Karuppiah Nagaraj,
  • P. Vijaya Kumar,
  • K. Raja,
  • P. Suganthi,
  • C. Muthukumar,
  • A. Stalin

摘要

Copper hydroxide nanorods (Cu(OH)₂ NRs) were successfully produced using ethanolic leaf extracts of Solanum pubescens utilizing a green synthesis technique. UV–Vis, FTIR, XRD, and SEM–EDX analysis revealed the development of orthorhombic, rod-shaped nanoparticles with an average size of ~ 50 nm. Cu(OH)₂ NRs showed significant antibacterial activity, with inhibition zones ranging from 8.55 ± 0.59 mm to 9.80 ± 0.68 mm against bacterial strains like S. aureus and K. pneumoniae, and 6.20 ± 0.43 mm to 7.90 ± 0.55 mm against fungal strains like C. albicans. The DPPH experiment demonstrated dose-dependent antioxidant activity, reaching 87.12 ± 5.87% at 80 µg/ml and an IC₅₀ value of 51.53 µg/ml. Cu(OH)₂ NRs caused up to 42.2% cell death in anticancer experiments against MCF-7 breast cancer cells at the highest dose tested (500 µg/mL). The synthesized Cu(OH)₂ nanorods exhibited strong antimicrobial activity, comparable to conventional antibiotics and significantly superior to the plant extract. Their broad-spectrum efficacy, eco-friendly synthesis, and effectiveness against resistant strains highlight their potential as alternative antimicrobial agents.