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<p>Solitary fibrous tumor (SFT) associated with hypoglycemia is termed Doege-Potter syndrome (DPS). It may be found in almost any site of the body, but most predominantly in the intra-thoracic region, and is a rare differential diagnosis of recurrent hypoglycemia. A 73-year-old, hypertensive, non-diabetic man presented with recurrent hypoglycemic episodes, and examination revealed diminished breath sounds in the right lower lung fields. Investigations demonstrated that the patient had a mass lesion in the right thorax. Excision of the mass lesion produced biopsy samples, and the histopathological examination of the tissue was suggestive of SFT. Patients with recurrent hypoglycemia must always be screened and treated for DPS. SFTs with non-insulin-induced hypoglycemia (NICTH) are likely to be malignant. Early diagnosis and a multidisciplinary approach are pivotal in the management of the disease. Complete surgical excision of the mass lesion is the standard of care for SFTs with DPS.</p>

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An Unusual Cause of Hypoglycemia: Doege-Potter Syndrome—A Case Report and Review of Literature

  • 期刊论文

  • 发表日期：

    2025年2月27日

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  • Ravisankar Palaniappan,
  • Suresh Kannan,
  • Pranav Prem,
  • Padma Priya Camalarajan

摘要

Solitary fibrous tumor (SFT) associated with hypoglycemia is termed Doege-Potter syndrome (DPS). It may be found in almost any site of the body, but most predominantly in the intra-thoracic region, and is a rare differential diagnosis of recurrent hypoglycemia. A 73-year-old, hypertensive, non-diabetic man presented with recurrent hypoglycemic episodes, and examination revealed diminished breath sounds in the right lower lung fields. Investigations demonstrated that the patient had a mass lesion in the right thorax. Excision of the mass lesion produced biopsy samples, and the histopathological examination of the tissue was suggestive of SFT. Patients with recurrent hypoglycemia must always be screened and treated for DPS. SFTs with non-insulin-induced hypoglycemia (NICTH) are likely to be malignant. Early diagnosis and a multidisciplinary approach are pivotal in the management of the disease. Complete surgical excision of the mass lesion is the standard of care for SFTs with DPS.