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<p>Invasive lobular breast cancer is a rare and special subtype of breast cancer which has a different clinical behaviour and is morphologically different from other subtypes. However, it is not any different in terms of outcome as compared to invasive ductal carcinoma. It accounts for 5–15% of the invasive breast cancers (Li et al. in Br J Cancer 93:1046-1052, 2005). Her 2 Neu positivity in invasive lobular cancers (ILCs) is even rarer and has been linked to adverse outcomes, although limited literature is available. Management of ILCs with Her 2 Neu positivity is according to standard multimodality breast cancer management guidelines. Here, we report a case report of an early-stage invasive lobular breast cancer with hormone receptor and Her 2 Neu positivity.</p>

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A Rare Case Report—an Early-Stage Invasive Lobular Carcinoma with Her 2 Neu Positivity

  • 期刊论文

  • 发表日期：

    2025年2月12日

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  • Preeti Grewal,
  • Geeta Kadayaprath,
  • Parul Sobti

摘要

Invasive lobular breast cancer is a rare and special subtype of breast cancer which has a different clinical behaviour and is morphologically different from other subtypes. However, it is not any different in terms of outcome as compared to invasive ductal carcinoma. It accounts for 5–15% of the invasive breast cancers (Li et al. in Br J Cancer 93:1046-1052, 2005). Her 2 Neu positivity in invasive lobular cancers (ILCs) is even rarer and has been linked to adverse outcomes, although limited literature is available. Management of ILCs with Her 2 Neu positivity is according to standard multimodality breast cancer management guidelines. Here, we report a case report of an early-stage invasive lobular breast cancer with hormone receptor and Her 2 Neu positivity.