Oncocytic Noninvasive Follicular Thyroid Neoplasm with Papillary-Like Nuclear Features: A Case Report

Noninvasive follicular thyroid neoplasm with papillary-like nuclear features (NIFTP) poses diagnostic challenges due to its rarity and distinctive histomorphological features. We report a case of oncocytic NIFTP in a 50-year-old lady with left thyroid swelling, emphasizing the difficulties encountered in both cytological and histological diagnosis. The case illustrates the importance of meticulous examination and awareness of updated diagnostic criteria, especially in distinguishing NIFTP from other thyroid neoplasms. Furthermore, we discuss the evolution of diagnostic guidelines, including the 2022 WHO classification, and the implications for clinical management and prognosis. Despite challenges, accurate diagnosis of NIFTP is crucial, given its favorable prognosis and minimal risk of recurrence or metastasis.