Objective <p>This study explores the impact of age and sexual and gender identity disclosure on health and quality of life among LGBT + individuals in Argentina, with a focus on the moderating role of age.</p> Methods <p>A cross-sectional survey was conducted in 2022 with LGBT + adults residing in Argentina. Participants completed validated measures assessing quality of life, depressive symptoms, and identity disclosure. Bivariate and regression analyses were used to examine age-specific differences and interaction effects.</p> Results <p>Older adults (aged 50 and over) reported lower levels of depressive symptoms, though no significant differences were found in quality of life or identity disclosure when compared to younger participants (ages 19–49). Greater identity disclosure was associated with better quality of life and fewer depressive symptoms, with a particularly strong association observed among older adults. Transgender participants reported lower quality of life and higher levels of depressive symptoms compared to their cisgender peers.</p> Conclusion <p>Identity disclosure plays a critical role in the well-being of LGBT + individuals, especially older adults. Age and identity-related factors should be carefully considered in the development of public health interventions and social policies targeting this community.</p> Social Policy Implications <p>These findings underscore the importance of promoting supportive environments for sexual and gender diversity in Argentina. Policies that reduce stigma—such as anti-discrimination legislation and public awareness campaigns—are essential to improving health outcomes for LGBT + populations.</p>