<p>Most African countries have committed to the structural transformation process in order to boost their economic development. This commitment to the structural transformation by African countries can influence positively or negatively the women’s labor market participation. The goal of this paper is to identify the effect of structural transformation on women’s participation in the labor market into African countries. We specified a dynamic panel and estimated with the generalized method of moments (GMM) in system. The data used come from the World Development Indicator (WDI) and observed over the period 1999–2022 of 33 African countries. Our results show that structural transformation has a positive effect on women’s participation in the labor market into African countries. The results also showed that education has a positive effect on women’s participation in the labor market into African countries. The integration of women into manufacturing companies specifically can contribute to women’s participation in economic life into African countries. Improving access of education for women can also contribute to women’s participation to labor market into African countries.</p>