Systemische Sklerose

Systemic sclerosis (SSc) is a complex, chronic autoimmune disease that can lead to fibrosis of both the skin and internal organs. The prognosis concerning the course of the disease is highly variable and depends, among other things, on organ involvement. Drug therapy has been improved through the use of new substances, which means that interstitial lung involvement, for example, which is associated with increased mortality, can be treated more effectively. Nevertheless, SSc remains a disease with high mortality and morbidity and further studies are needed to improve drug therapy.