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<p>This case report presents the application of FOLactis, a lactic acid bacterium in situ vaccine, in the treatment of a lung adenocarcinoma patient who presented with malignant pleural effusion (MPE). An adult patient diagnosed with lung adenocarcinoma complicated by malignant pleural effusion (MPE) experienced favorable outcomes following the administration of intracavitary infusion of FOLactis, as conventional therapeutic approaches failed to yield satisfactory results. One month after the administration of FOLactis treatment, a subsequent CT examination revealed the complete resolution of malignant pleural effusion (MPE).</p>

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Intracavitary infusion of FOLactis Lactobacillus leads to disappearance of MPE in patient with advanced lung adenocarcinoma

  • 期刊论文

  • 出版模式：

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  • 发表日期：

    2025年11月3日

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  • Mingzhen Zhou,
  • Juan Zhang,
  • Sihui Zhu,
  • Yan Zhao,
  • Baorui Liu,
  • Jie Shen

摘要

This case report presents the application of FOLactis, a lactic acid bacterium in situ vaccine, in the treatment of a lung adenocarcinoma patient who presented with malignant pleural effusion (MPE). An adult patient diagnosed with lung adenocarcinoma complicated by malignant pleural effusion (MPE) experienced favorable outcomes following the administration of intracavitary infusion of FOLactis, as conventional therapeutic approaches failed to yield satisfactory results. One month after the administration of FOLactis treatment, a subsequent CT examination revealed the complete resolution of malignant pleural effusion (MPE).