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Background <p>Carotid body tumors (CBTs) are rare paragangliomas with an incidence of 1–2 per 100,000 individuals. While surgical resection remains the standard treatment, postoperative recurrence poses a clinical challenge.</p> Case presentation <p>We describe a 49-year-old female with recurrent CBT involving the jugular foramen, managed with IGRT (60 Gy/30 fractions) and 4 cycles of CVD chemotherapy. Post-treatment RECIST evaluation revealed stable disease, supporting chemoradiotherapy as a salvage option for anatomically complex recurrences.</p> Conclusion <p>This case underscores the necessity for standardized protocols and further research to validate multimodal therapy in recurrent CBTs.</p>

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Chemoradiotherapy for recurrent CBTs case report

  • 期刊论文

  • 出版模式：

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  • 发表日期：

    2025年8月11日

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  • Guangyu Liu,
  • Shuangyan Zhao,
  • Jiankai Wang,
  • Xiaoyu Duan,
  • Hongyi Cai

摘要

Background

Carotid body tumors (CBTs) are rare paragangliomas with an incidence of 1–2 per 100,000 individuals. While surgical resection remains the standard treatment, postoperative recurrence poses a clinical challenge.

Case presentation

We describe a 49-year-old female with recurrent CBT involving the jugular foramen, managed with IGRT (60 Gy/30 fractions) and 4 cycles of CVD chemotherapy. Post-treatment RECIST evaluation revealed stable disease, supporting chemoradiotherapy as a salvage option for anatomically complex recurrences.

Conclusion

This case underscores the necessity for standardized protocols and further research to validate multimodal therapy in recurrent CBTs.