<p>Iron oxide nanostructures have been grown biogenically, using <i>Ageratum conyzoides</i> L. extract, and characterized in terms of XRD, XPS, EDX, IR, UV, SEM, Zeta potential and HR-TEM studies. The SEM and TEM studies revealed that it consists of irregular cubic-shaped structures of 34–50&#xa0;nm size. The synthesized materials exhibited antidiabetic and antioxidant potential with an IC₅₀ of 41.74 ± 0.6&#xa0;µg/mL and an IC₅₀ of 61.8&#xa0;µg/mL, respectively. It exhibited anticancer potential against the MCF-7 cell line, with the IC<sub>50</sub> value of 373.08&#xa0;µg/mL in the in vitro cytotoxicity cell study of the biogenic synthesis of iron oxide nanostructures.</p>

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Biogenic Growth of Iron Oxide Nanostructure using Ageratum conyzoides L. Plant Extract: In Vitro Antioxidant, Anticancer, and Antidiabetic Potential

  • Intakhab Alam,
  • Nazish Siddiqui,
  • Naved Haider,
  • Om Prakash,
  • Anil Kumar,
  • Shah Raj Ali

摘要

Iron oxide nanostructures have been grown biogenically, using Ageratum conyzoides L. extract, and characterized in terms of XRD, XPS, EDX, IR, UV, SEM, Zeta potential and HR-TEM studies. The SEM and TEM studies revealed that it consists of irregular cubic-shaped structures of 34–50 nm size. The synthesized materials exhibited antidiabetic and antioxidant potential with an IC₅₀ of 41.74 ± 0.6 µg/mL and an IC₅₀ of 61.8 µg/mL, respectively. It exhibited anticancer potential against the MCF-7 cell line, with the IC50 value of 373.08 µg/mL in the in vitro cytotoxicity cell study of the biogenic synthesis of iron oxide nanostructures.