<p>Diabetes mellitus is a chronic metabolic disorder characterised by elevated blood glucose levels, resulting from either inadequate insulin secretion from pancreatic beta cells (type 1 diabetes) or reduced insulin sensitivity in the body (type 2 diabetes). Health complications associated with diabetes and adverse effects of traditional treatment strategies create clinical and socioeconomic burden, which impede sustainable diabetes management. In this regard, nanotechnology gains tremendous interest as a leading contributor in the biomedical field. Especially in diabetes management nanomaterials are highly promising as diagnostic and therapeutic agents. This article shed light in to the recent progress of nano-based antidiabetic agents that enhance therapeutic outcomes with precision and controlled drug release while ensuring minimization of side effects. The article progresses with the discussion on the limitations of conventional therapies, advantages of using nanomaterials as drug carriers, current challenges of nano-based antidiabetic strategies and the future applications of nanotechnology in diabetes care.</p>

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Nanomaterials in Diabetes Care: Recent Trends in Precision and Controlled Treatment Strategies

  • Meera Varghese,
  • Yasmin Shaik Haroon,
  • Amaljith Kumar,
  • Manoj Balachandran

摘要

Diabetes mellitus is a chronic metabolic disorder characterised by elevated blood glucose levels, resulting from either inadequate insulin secretion from pancreatic beta cells (type 1 diabetes) or reduced insulin sensitivity in the body (type 2 diabetes). Health complications associated with diabetes and adverse effects of traditional treatment strategies create clinical and socioeconomic burden, which impede sustainable diabetes management. In this regard, nanotechnology gains tremendous interest as a leading contributor in the biomedical field. Especially in diabetes management nanomaterials are highly promising as diagnostic and therapeutic agents. This article shed light in to the recent progress of nano-based antidiabetic agents that enhance therapeutic outcomes with precision and controlled drug release while ensuring minimization of side effects. The article progresses with the discussion on the limitations of conventional therapies, advantages of using nanomaterials as drug carriers, current challenges of nano-based antidiabetic strategies and the future applications of nanotechnology in diabetes care.