Scholarlink

<p>Triazine-derived functional materials represent a promising class of compounds due to their diverse biological activities. In this study, novel triazine-based ligands (PTAPTP and PTAMTP) and their nickel complexes (Ni-PTAPTP and Ni-PTAMTP) were synthesized and systematically characterized using <sup>1</sup>H NMR, <sup>13</sup>C NMR, UV–Vis, and FT–IR spectroscopy to elucidate structure–property relationships. The effects of metal coordination on electronic transitions and bonding features were investigated, alongside the influence of ligand substituents on electronic behavior and coordination dynamics. Biological evaluation revealed significant antioxidant, antifungal, and antibacterial activities. Among the tested compounds, the Ni‑PTAMTP complex exhibited the strongest antioxidant potential with an IC₅₀ value of 87.04&#xa0;µg/ml. Ni‑PTAMTP also demonstrated the highest antibacterial efficacy against <i>Staphylococcus aureus</i> (16.25 ± 0.35&#xa0;mm), while its ligand PTAMTP showed notable activity (12.25 ± 0.35&#xa0;mm). Antifungal assays indicated that Ni‑PTAMTP produced the largest inhibition zone against <i>Candida albicans</i> (18.8 ± 0.14&#xa0;mm), whereas Ni‑PTAPTP was most effective against <i>Aspergillus niger</i> (18.75 ± 0.35&#xa0;mm). These findings highlight the critical role of structural modifications in triazine ligands for tuning biological performance, offering valuable insights for the design of multifunctional bioactive materials.</p>

错误：搜索内容不能为空，请输入英文关键词
错误：关键词超出字数限制，请精简
高级检索

Two Nickel Complexes Bearing A Triazine Moiety: Synthesis, Antioxidant, and Antimicrobial Activities

  • 期刊论文

  • 发表日期：

    2026年2月19日

查看全文
  • Avila Josephine B,
  • Eshitha Mariam Mathew,
  • G. Kaladevi,
  • Alphonse Lazar,
  • Ashwini A,
  • Subash C.B. Gopinath,
  • Mary Teresita V.

摘要

Triazine-derived functional materials represent a promising class of compounds due to their diverse biological activities. In this study, novel triazine-based ligands (PTAPTP and PTAMTP) and their nickel complexes (Ni-PTAPTP and Ni-PTAMTP) were synthesized and systematically characterized using 1H NMR, 13C NMR, UV–Vis, and FT–IR spectroscopy to elucidate structure–property relationships. The effects of metal coordination on electronic transitions and bonding features were investigated, alongside the influence of ligand substituents on electronic behavior and coordination dynamics. Biological evaluation revealed significant antioxidant, antifungal, and antibacterial activities. Among the tested compounds, the Ni‑PTAMTP complex exhibited the strongest antioxidant potential with an IC₅₀ value of 87.04 µg/ml. Ni‑PTAMTP also demonstrated the highest antibacterial efficacy against Staphylococcus aureus (16.25 ± 0.35 mm), while its ligand PTAMTP showed notable activity (12.25 ± 0.35 mm). Antifungal assays indicated that Ni‑PTAMTP produced the largest inhibition zone against Candida albicans (18.8 ± 0.14 mm), whereas Ni‑PTAPTP was most effective against Aspergillus niger (18.75 ± 0.35 mm). These findings highlight the critical role of structural modifications in triazine ligands for tuning biological performance, offering valuable insights for the design of multifunctional bioactive materials.