Scholarlink

<p>Pathogenic infections, particularly foodborne diseases have emerged as a growing concern globally. Gold nanoparticles (AuNPs) immobilized zirconium metal-organic framework/multi-walled carbon nanotube (Au@Zr-BDC/MWCNT) ternary composite as a sensing platform for the accurate identification of <i>staphylococcus aureus</i> (<i>SPA</i>). Citrate-capped AuNPs were self-assembled onto the Zr-BDC/MWCNT surface, and EDC/NHS chemistry was employed to covalently bridge antibody to the Au@Zr-BDC/MWCNT surface. Comprehensive characterizations of the as-synthesized materials were conducted using various analytical techniques. Transmission electron microscopic images showed that the Zr-MOF particles with a mean diameter of around 90&#xa0;nm were dispersed on the MWCNT surface. The developed Au@Zr-BDC/MWCNT immune-sensing platform demonstrated exceptional specificity toward <i>SPA</i>with a detecting concentration ranging from 6.0 to 6.5 × 10<sup>6</sup>CFU/mL with a detection limit of 4 CFU/mL. The developed immunosensor illustrated on-site detection of SPA in milk samples and exhibited rapid response, selectivity, and easy operation.</p>

错误：搜索内容不能为空，请输入英文关键词
错误：关键词超出字数限制，请精简
高级检索

Gold-decorated MOF/carbon Nanotube Ternary Hybrid as a Sensitive Electrochemical Biosensor for Staphylococcus Aureus

  • 期刊论文

  • 发表日期：

    2026年1月16日

查看全文
  • N. Gokila,
  • Yuvaraj Haldorai,
  • Ramasamy Thangavelu Rajendra Kumar

摘要

Pathogenic infections, particularly foodborne diseases have emerged as a growing concern globally. Gold nanoparticles (AuNPs) immobilized zirconium metal-organic framework/multi-walled carbon nanotube (Au@Zr-BDC/MWCNT) ternary composite as a sensing platform for the accurate identification of staphylococcus aureus (SPA). Citrate-capped AuNPs were self-assembled onto the Zr-BDC/MWCNT surface, and EDC/NHS chemistry was employed to covalently bridge antibody to the Au@Zr-BDC/MWCNT surface. Comprehensive characterizations of the as-synthesized materials were conducted using various analytical techniques. Transmission electron microscopic images showed that the Zr-MOF particles with a mean diameter of around 90 nm were dispersed on the MWCNT surface. The developed Au@Zr-BDC/MWCNT immune-sensing platform demonstrated exceptional specificity toward SPAwith a detecting concentration ranging from 6.0 to 6.5 × 106CFU/mL with a detection limit of 4 CFU/mL. The developed immunosensor illustrated on-site detection of SPA in milk samples and exhibited rapid response, selectivity, and easy operation.