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<p>This study explores the potential of using copper nanoparticles in cell-inhibitory studies, including early research and evaluation of specific techniques. The electric explosive wire (EEW) method is a simple, chemical-free method used to synthesize copper nanoparticles. The wire is blown through a voltage divider device, converting it into steam and condensing it into a deionized liquid. The wire’s evaporation and ionization generate enough energy for deposition, resulting in nanoparticles with a diameter of less than 100&#xa0;nm. The study focuses on the structural properties of copper nanoparticles using X-ray diffraction (XRD) and characterizations of the copper nanopowders. The XRD patterns showed a copper peak at (2<i>θ</i>&#xa0;≈&#xa0;43.98, 50.41, and 74.18), belonging to the (111), (200), and (220) planes, respectively. The FE-SEM electron microscopy scan revealed the presence of copper nanoparticles distributed on glass substrates, with an average particle size from 9 to 12&#xa0;nm, making them acceptable for biological applications. The morphology of copper nanoparticles was examined using transmission electron microscopy (TEM) and atomic force microscopy (AFM). The copper nanoparticles produced exhibit a grain size distribution of 32.97&#xa0;nm, a root mean square roughness (RMS) Rq of 17.21&#xa0;nm, and an average roughness (Ra) of 13.28&#xa0;nm. The zeta potential of the system was determined to be −&#xa0;37.28&#xa0;mV, indicating that the microemulsion droplets carry a negative charge. Two types of bacteria were prepared according to the study: Gram-negative <i>Escherichia&#xa0;coli</i> bacteria and <i>Staphylococcus aureus</i> bacteria. The nanopowder produced by blasting copper wires onto glass dishes demonstrated a higher inhibition rate than the liquid, due to the larger copper nanoparticles contained in the powder killing the bacteria. Copper nanoparticles exhibit significant antibacterial activity due to multiple mechanisms, making them a promising agent in combating bacteria, including strains resistant to conventional antibiotics.</p>

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Synthesis and Characterization of Cu Nanoparticles by Wire Explosion Technique for Antibacterial Applications

  • 期刊论文

  • 发表日期：

    2025年7月3日

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  • Bilal K. Al-Rawi,
  • Safaa Mustafa Hameed,
  • Sundus Alzuhairi

摘要

This study explores the potential of using copper nanoparticles in cell-inhibitory studies, including early research and evaluation of specific techniques. The electric explosive wire (EEW) method is a simple, chemical-free method used to synthesize copper nanoparticles. The wire is blown through a voltage divider device, converting it into steam and condensing it into a deionized liquid. The wire’s evaporation and ionization generate enough energy for deposition, resulting in nanoparticles with a diameter of less than 100 nm. The study focuses on the structural properties of copper nanoparticles using X-ray diffraction (XRD) and characterizations of the copper nanopowders. The XRD patterns showed a copper peak at (2θ ≈ 43.98, 50.41, and 74.18), belonging to the (111), (200), and (220) planes, respectively. The FE-SEM electron microscopy scan revealed the presence of copper nanoparticles distributed on glass substrates, with an average particle size from 9 to 12 nm, making them acceptable for biological applications. The morphology of copper nanoparticles was examined using transmission electron microscopy (TEM) and atomic force microscopy (AFM). The copper nanoparticles produced exhibit a grain size distribution of 32.97 nm, a root mean square roughness (RMS) Rq of 17.21 nm, and an average roughness (Ra) of 13.28 nm. The zeta potential of the system was determined to be − 37.28 mV, indicating that the microemulsion droplets carry a negative charge. Two types of bacteria were prepared according to the study: Gram-negative Escherichia coli bacteria and Staphylococcus aureus bacteria. The nanopowder produced by blasting copper wires onto glass dishes demonstrated a higher inhibition rate than the liquid, due to the larger copper nanoparticles contained in the powder killing the bacteria. Copper nanoparticles exhibit significant antibacterial activity due to multiple mechanisms, making them a promising agent in combating bacteria, including strains resistant to conventional antibiotics.