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<p>Diabetes mellitus (DM) is a metabolic chronic disease distinguished by unexpectedly and inappropriately elevated levels of glucose in the blood of any individual. It has various categories depending on various causative agents or differences in the etiology of each class. Diabetes is regrettably one of the most prevalent diseases worldwide and continues to be the seventh leading cause of death in the USA. To overcome this chronic disease, significant work has been done through decades leading to various research, different management techniques and a majorly large amount of work has been done in the usage of nanotechnology. This initiative leads to the production of various formulations for the treatment of diabetes using nanotechnology. Examples of these products are insulin liposomes, insulin noisome, and gold or zinc oxide nanoparticles which show greater therapeutic efficacy and subsequently good control of DM, and these are also used for precise drug deliveries. This review covers the use of different types of nanoparticles for enhanced delivery of various hypoglycemic agents in comparison to traditional therapies. Many new research and studies about antidiabetic drugs and nanotechnology are still going on and would be so profitable in managing and treating DM.</p>

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Nanocarrier-based Drug Delivery Systems: A Way to Effective Diabetes Management

  • 期刊论文

  • 出版模式：

    开放获取

  • 发表日期：

    2025年3月20日

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  • Najlaa Hamed S Almohmadi,
  • Ankita Tiwari,
  • Tushar Chaudhary,
  • Ekta,
  • Rakesh K Sindhu,
  • M. Arockia Babu,
  • Asmaa S. A. Yassen,
  • Athanasios Alexiou,
  • Marios Papadakis,
  • Gaber El-Saber Batiha

摘要

Diabetes mellitus (DM) is a metabolic chronic disease distinguished by unexpectedly and inappropriately elevated levels of glucose in the blood of any individual. It has various categories depending on various causative agents or differences in the etiology of each class. Diabetes is regrettably one of the most prevalent diseases worldwide and continues to be the seventh leading cause of death in the USA. To overcome this chronic disease, significant work has been done through decades leading to various research, different management techniques and a majorly large amount of work has been done in the usage of nanotechnology. This initiative leads to the production of various formulations for the treatment of diabetes using nanotechnology. Examples of these products are insulin liposomes, insulin noisome, and gold or zinc oxide nanoparticles which show greater therapeutic efficacy and subsequently good control of DM, and these are also used for precise drug deliveries. This review covers the use of different types of nanoparticles for enhanced delivery of various hypoglycemic agents in comparison to traditional therapies. Many new research and studies about antidiabetic drugs and nanotechnology are still going on and would be so profitable in managing and treating DM.