Synthesis and Antibiofilm Activity of Silver Nanoparticles Fabricated Sodium Alginate–Based Nanocomposite Film

In order to meet the rising demand for silver nanoparticles across a variety of industries, it is necessary to devise a technique of synthesis that is not only inexpensive but also economically viable and kind to the natural environment. We employed our previous study on the leaves of the Lantana camara plant to perform synthesis of AgNPs, which were then incorporated into a biofilm using sodium alginate and evaluated for their ability to inhibit the growth of bacterial and fungal biofilms. At concentrations of 1 mM and 5 mM silver nitrate, it was possible to successfully synthesize bioactive and biofilms of sodium alginate. These biofilms consisted of silver nanoparticles. It was discovered that the average thickness of the biofilm ranged from 1.03 to 1.1 mm when the silver nitrate concentration was between 1 and 5 mM. It has been shown that biofilms are resilient in both alkaline and acidic conditions. In addition, the biofilms all showed a low percentage of moisture retention. The water solubility of biofilms with a concentration of 1 mM silver nitrate was much lower than that of biofilms with a concentration of 5 mM silver nitrate. In addition, the gram-positive bacteria Staphylococcus epidermis and Staphylococcus hemolyticus were inhibited by the film. Both Staphylococcus epidermis and Staphylococcus hemolyticus have a potent biofilm effect against every kind of biofilm. Nevertheless, these biofilms can be further explored to identify their medical and other additional applications.