<p>To clarify the spatial distribution of heavy metals and assess their potential health risks under the influence of seawater intrusion, 48 groundwater samples were collected from three confined aquifers in the coastal zone of Weifang, China. The concentrations of 13 heavy metals were analyzed. Spatial distribution patterns and inter-element correlations were assessed, and Cl^- was used as a proxy to explore the impact of seawater intrusion on heavy metal enrichment. Additionally, a quantitative health risk assessment was performed following USEPA guidelines. The results show that Fe and Mn concentrations exceed the standards. The distribution of heavy metals exhibits obvious stratigraphic and regional differences, with high spatial heterogeneity. The shallow aquifer is significantly influenced by anthropogenic pollution and seawater intrusion along paleochannel. The middle aquifer is the primary layer for heavy metal accumulation. The deep aquifer is more controlled by geological background conditions. Production activities have not caused large-scale vertical water quality exchange. Strong correlations were found between Cl^- and certain heavy metals (Cd, Mn, Co, V), suggesting that seawater intrusion may enhance the mobilization of specific contaminants. Health risk assessment indicates that ingestion is the primary exposure pathway, with adults facing higher health risks than children. The non-carcinogenic risk is mainly attributed to Mn, with Aquifer II showing higher risk, primarily in coastal region. The carcinogenic risk is mainly attributed to Cd and As, with Aquifer I showing higher risk. These findings provide a scientific basis for groundwater quality protection and pollution control in coastal aquifer systems.</p>