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Background <p>Upper gastrointestinal bleeding is an important gastrointestinal emergency medical condition; however, there is a lack of multi-centre national data on this condition for India. Hence, the Indian Society of Gastroenterology (ISG) constituted a task force on upper gastrointestinal bleeding (UGIB) to collect and create a database representative of every part of India. The aim of this pan-India multi-centre study was to determine the etiology and clinical characteristics of UGIB in India and to identify the risk factors that determine the overall outcome in these patients.</p> Methods <p>In consultation with the members of the task force, a protocol and case record form were developed and members of the ISG were invited to participate in data collection. Overall, 93 centres from different parts of India joined this study. A prospective longitudinal cohort study was designed and data was acquired between October 2014 and September 2018. All 93 participating centres were instructed to recruit patients with UGIB as per the approved protocol. All patients were followed up for 30&#xa0;days either telephonically or during a hospital visit for re-bleeding rate up to 30&#xa0;days from the first presentation, requirement for surgery and 30-day mortality. Statistical Package for the Social Sciences (SPSS) software (version 17.0, SPSS, Chicago, IL., USA) was used for all statistical analyses.</p> Results <p>Of 12,500 patients, 10,564 patients with UGIB were&#xa0;included in this study, 6450 (61.1%) and 4114 (38.9%) had non-variceal UGIB and variceal UGIB, respectively. Overall, 92 (1.4%) had rebleeding, 20 (0.3%) had surgery and 184 (2.8%) had mortality in non-variceal UGIB patients. Of variceal UGIB, 67 (1.6%) had rebleeding within 30&#xa0;days, five (0.12%) variceal upper gastrointestinal bleeding (VUGIB) underwent surgery and 151 (3.67%) was the mortality rate among the VUGIB bleed.</p> Conclusions <p>This is the first large national database on patients with UGIB describing their causes, treatment outcomes, complications and predictors of complications.</p> Graphical Abstract <p></p>

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A nationwide multi-centre survey of 12,500 cases of upper gastrointestinal bleeding: A report of Indian Society of Gastroenterology Task Force on acute upper gastrointestinal bleed

  • 期刊论文

  • 发表日期：

    2026年6月1日

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  • Shivaram Prasad Singh,
  • Manoj K. Sahu,
  • Avinash Balekuduru,
  • Govind K. Makharia,
  • Saroj K. Sinha,
  • Philip Augustine,
  • Varghese Thomas,
  • Manu Tandan,
  • Shrikant Mukewar,
  • Sujoy Pal,
  • Bailuru V. Tantry,
  • Mahesh K. Goenka,
  • Rakesh Kochhar,
  • Pravin Rathi,
  • Sri P. Misra,
  • Ebby G. Simon,
  • Ajay K. Jain,
  • V. G. Mohan Prasad,
  • Rajkumar P. Wadhwa,
  • Sathyaprakash S. Bonthala,
  • Vinod K. Mishra,
  • Mathew Philip,
  • Sandeep Nijhawan,
  • Manas K. Panigrahi,
  • Kanishka Uthansingh,
  • Harsh Udawat,
  • Bhabadev Goswami,
  • Krishnadas Devadas,
  • Gautam Ray,
  • Satheesh Rao,
  • Rajiv Baijal,
  • Robert P. Panakkal,
  • Dipak Shah,
  • Abhinav Sharm,
  • Mukesh Agarwala,
  • Sanjay Kumar,
  • Manisha Dwivedi,
  • Karam R. Singh,
  • Pradip Bhaumik,
  • Baldev S. Rana,
  • Sushant K. Sethi,
  • Venkatakrishnan H. Iyer,
  • Anup K. Das,
  • Devendra Singh,
  • L.R.S Girinadh,
  • Venu H. Aradya,
  • Sunil Dadhich,
  • Reuben T. Kurien,
  • Ramesh K. Bhashyakarla,
  • Joy Varghese,
  • Srinivas Nistala,
  • Balakrishnan S. Ramakrishna,
  • Mahesh Gupta,
  • Harish Kareem,
  • Amitava Goswami,
  • Sandeep Pandey,
  • Meghraj Ingle,
  • Mrunmaya Panda,
  • Laxmikant Desai,
  • Abid Sattar,
  • Abhijit Deshmukh,
  • Sanjeev S. Khanna,
  • Prakash Zacharias,
  • Suneel C. Mahadasyam,
  • Jayanta Mukherjee,
  • Manish S. Bhatnagar,
  • Shivaprasad B,
  • Manoj Lahoti,
  • Amol Bapaye,
  • Jaydip Sarkar,
  • Suresh Shenoy,
  • Doraiswami Babu Vinish,
  • Dinesh Muthuluru,
  • Rakesh K. Barik

摘要

Background

Upper gastrointestinal bleeding is an important gastrointestinal emergency medical condition; however, there is a lack of multi-centre national data on this condition for India. Hence, the Indian Society of Gastroenterology (ISG) constituted a task force on upper gastrointestinal bleeding (UGIB) to collect and create a database representative of every part of India. The aim of this pan-India multi-centre study was to determine the etiology and clinical characteristics of UGIB in India and to identify the risk factors that determine the overall outcome in these patients.

Methods

In consultation with the members of the task force, a protocol and case record form were developed and members of the ISG were invited to participate in data collection. Overall, 93 centres from different parts of India joined this study. A prospective longitudinal cohort study was designed and data was acquired between October 2014 and September 2018. All 93 participating centres were instructed to recruit patients with UGIB as per the approved protocol. All patients were followed up for 30 days either telephonically or during a hospital visit for re-bleeding rate up to 30 days from the first presentation, requirement for surgery and 30-day mortality. Statistical Package for the Social Sciences (SPSS) software (version 17.0, SPSS, Chicago, IL., USA) was used for all statistical analyses.

Results

Of 12,500 patients, 10,564 patients with UGIB were included in this study, 6450 (61.1%) and 4114 (38.9%) had non-variceal UGIB and variceal UGIB, respectively. Overall, 92 (1.4%) had rebleeding, 20 (0.3%) had surgery and 184 (2.8%) had mortality in non-variceal UGIB patients. Of variceal UGIB, 67 (1.6%) had rebleeding within 30 days, five (0.12%) variceal upper gastrointestinal bleeding (VUGIB) underwent surgery and 151 (3.67%) was the mortality rate among the VUGIB bleed.

Conclusions

This is the first large national database on patients with UGIB describing their causes, treatment outcomes, complications and predictors of complications.

Graphical Abstract