Background <p>Temporomandibular disorders (TMDs) are musculoskeletal conditions associated with pain, functional limitation, and psychosocial impairment, significantly affecting oral health-related quality of life (OHRQoL).</p> Aim <p>To evaluate OHRQoL in patients with TMD compared with healthy controls and to assess changes over a 6-month follow-up period.</p> Materials and methods <p>This prospective observational cohort study included 79 participants (39 TMD patients and 40 controls). Diagnosis was established using DC/TMD criteria. OHRQoL was assessed using OHIP-14 at baseline and 6 months in the TMD group and once in controls. Clinical variables included pain severity (GCPS-R), maximum mouth opening (MMO), and joint-related dysfunctions. Statistical analysis included group comparisons and exploratory linear regression.</p> Results <p>Baseline OHIP-14 scores were significantly higher in TMD patients compared with controls (28.18 ± 4.31 vs. 3.98 ± 0.95; <i>p</i> &lt; 0.001). OHIP-14 scores in the TMD group were significantly lower at 6 months than at baseline (4.97 ± 1.12 vs. 28.18 ± 4.31; <i>p</i> &lt; 0.001). Pain severity, reduced maximum mouth opening, female gender, and closed lock were significantly associated with poorer OHRQoL. In multivariate analysis, pain severity emerged as the strongest predictor of OHIP-14 scores (β = 6.5, <i>p</i> &lt; 0.001; R² = 0.62).</p> Conclusion <p>TMD was associated with markedly impaired OHRQoL, with pain severity and functional limitation showing the strongest associations. Although significant improvement was observed at 6 months, findings represent temporal associations due to the observational design.</p>

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Oral Health-Related Quality of Life in Patients with Temporomandibular Disorders: A Prospective Cohort Study with 6-Month Follow-Up

  • Jimish Desai

摘要

Background

Temporomandibular disorders (TMDs) are musculoskeletal conditions associated with pain, functional limitation, and psychosocial impairment, significantly affecting oral health-related quality of life (OHRQoL).

Aim

To evaluate OHRQoL in patients with TMD compared with healthy controls and to assess changes over a 6-month follow-up period.

Materials and methods

This prospective observational cohort study included 79 participants (39 TMD patients and 40 controls). Diagnosis was established using DC/TMD criteria. OHRQoL was assessed using OHIP-14 at baseline and 6 months in the TMD group and once in controls. Clinical variables included pain severity (GCPS-R), maximum mouth opening (MMO), and joint-related dysfunctions. Statistical analysis included group comparisons and exploratory linear regression.

Results

Baseline OHIP-14 scores were significantly higher in TMD patients compared with controls (28.18 ± 4.31 vs. 3.98 ± 0.95; p < 0.001). OHIP-14 scores in the TMD group were significantly lower at 6 months than at baseline (4.97 ± 1.12 vs. 28.18 ± 4.31; p < 0.001). Pain severity, reduced maximum mouth opening, female gender, and closed lock were significantly associated with poorer OHRQoL. In multivariate analysis, pain severity emerged as the strongest predictor of OHIP-14 scores (β = 6.5, p < 0.001; R² = 0.62).

Conclusion

TMD was associated with markedly impaired OHRQoL, with pain severity and functional limitation showing the strongest associations. Although significant improvement was observed at 6 months, findings represent temporal associations due to the observational design.