Oral Health-Related Quality of Life in Patients with Temporomandibular Disorders: A Prospective Cohort Study with 6-Month Follow-Up
摘要
Temporomandibular disorders (TMDs) are musculoskeletal conditions associated with pain, functional limitation, and psychosocial impairment, significantly affecting oral health-related quality of life (OHRQoL).
AimTo evaluate OHRQoL in patients with TMD compared with healthy controls and to assess changes over a 6-month follow-up period.
Materials and methodsThis prospective observational cohort study included 79 participants (39 TMD patients and 40 controls). Diagnosis was established using DC/TMD criteria. OHRQoL was assessed using OHIP-14 at baseline and 6 months in the TMD group and once in controls. Clinical variables included pain severity (GCPS-R), maximum mouth opening (MMO), and joint-related dysfunctions. Statistical analysis included group comparisons and exploratory linear regression.
ResultsBaseline OHIP-14 scores were significantly higher in TMD patients compared with controls (28.18 ± 4.31 vs. 3.98 ± 0.95; p < 0.001). OHIP-14 scores in the TMD group were significantly lower at 6 months than at baseline (4.97 ± 1.12 vs. 28.18 ± 4.31; p < 0.001). Pain severity, reduced maximum mouth opening, female gender, and closed lock were significantly associated with poorer OHRQoL. In multivariate analysis, pain severity emerged as the strongest predictor of OHIP-14 scores (β = 6.5, p < 0.001; R² = 0.62).
ConclusionTMD was associated with markedly impaired OHRQoL, with pain severity and functional limitation showing the strongest associations. Although significant improvement was observed at 6 months, findings represent temporal associations due to the observational design.