<p>Salivary gland disorders are a diverse group of neoplastic and non-neoplastic lesions with varied clinical and histopathological presentations. Understanding their demographic distribution and pathological characteristics would provide better insight into their etiopathogenesis and aid in improved diagnosis and management. To determine the prevalence of salivary gland disorders at Saveetha Dental College, Chennai, analyze their demographic distribution, and evaluate the clinicopathological spectrum of these lesions. A retrospective study was conducted on salivary gland disorders diagnosed between May 2021 and December 2023. Data regarding age, gender, biopsy type, tumor site, laterality, and histopathological diagnosis were retrieved from online hospital records. Descriptive statistical analysis was performed using SPSS V29. Among 2626 cases, 104 salivary gland disorders were identified. Among 33 salivary gland tumors, 45.4% were benign, with Pleomorphic adenoma (60%) being the most common, and 54.5% were malignant, predominantly Adenoid cystic carcinoma (38.9%). Mucocele was the most frequent non-neoplastic disorder. The palatal mucosa was the most common site for benign tumors, whereas malignant tumors predominantly involved the alveolar mucosa. The mean age of affected individuals was 29.4 years, with the highest prevalence (33.6%) in the 19–30 age group. Salivary gland disorders had a prevalence of 3.96%, with Pleomorphic adenoma as the most common benign tumor, Adenoid cystic carcinoma as the predominant malignant tumor, and Mucocele was the most frequent non-neoplastic lesion.</p>