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Aim <p>Surgical extraction of lower third molars cause pain, trismus, and swelling, leading to discomfort and work disruptions. To mitigate this, our study evaluated the efficacy of two combinations: 2% Lignocaine with 1:80,000 adrenaline with 40mg Triamcinolone Acetonide, and 0.5% Bupivacaine with 40 mg of Triamcinolone Acetonide.</p> Materials and Methods <p>An institutional, single-blinded randomised clinical pilot study was conducted involving three groups, each consisting of 25 subjects. The control group subjects underwent surgical extraction while receiving 2% Lignocaine with 1:80,000 ADR only. In contrast, the study group subjects were administered a novel combination named “Wonder Mix” during the inferior alveolar nerve block. The study was analyzed based on VAS pain scores at 1st, 3rd, and 7th-day intervals and the total consumption of rescue analgesics.</p> Result <p>Group 1 exhibited the highest mean pain scores, whereas Groups 2 and 3 reported lower scores on all observation days. Moreover, Group 1 had the highest mean analgesic usage, with Groups 2 and 3 using much less.</p> Conclusion <p>This study demonstrates the significant benefits of combining Triamcinolone Acetonide with local anesthetics for managing postoperative pain in lower third molar surgeries as patients in the study groups experienced minimal postoperative pain and reduced analgesic intake.</p>

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Combining Local Anaesthetics with Triamcinolone Acetonide: Applications in Lower Third Molar Surgeries

  • 期刊论文

  • 发表日期：

    2026年3月10日

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  • Avni Maheshwari,
  • Abhishek Rupani,
  • Nishant Gupta,
  • Mitesh Ramani,
  • Garima Singh,
  • Mukul Mathur,
  • Abhishek Gupta

摘要

Aim

Surgical extraction of lower third molars cause pain, trismus, and swelling, leading to discomfort and work disruptions. To mitigate this, our study evaluated the efficacy of two combinations: 2% Lignocaine with 1:80,000 adrenaline with 40mg Triamcinolone Acetonide, and 0.5% Bupivacaine with 40 mg of Triamcinolone Acetonide.

Materials and Methods

An institutional, single-blinded randomised clinical pilot study was conducted involving three groups, each consisting of 25 subjects. The control group subjects underwent surgical extraction while receiving 2% Lignocaine with 1:80,000 ADR only. In contrast, the study group subjects were administered a novel combination named “Wonder Mix” during the inferior alveolar nerve block. The study was analyzed based on VAS pain scores at 1st, 3rd, and 7th-day intervals and the total consumption of rescue analgesics.

Result

Group 1 exhibited the highest mean pain scores, whereas Groups 2 and 3 reported lower scores on all observation days. Moreover, Group 1 had the highest mean analgesic usage, with Groups 2 and 3 using much less.

Conclusion

This study demonstrates the significant benefits of combining Triamcinolone Acetonide with local anesthetics for managing postoperative pain in lower third molar surgeries as patients in the study groups experienced minimal postoperative pain and reduced analgesic intake.