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Objective <p>To present a rare case of calcifying odontogenic cyst (COC), highlighting its clinical, radiographic, and histopathological characteristics, as well as the challenges in management and follow-up.</p> Case Report <p>A 20-year-old male patient presented with progressive tooth mobility in the mandibular anterior region. Cone beam computed tomography (CBCT) revealed a well-defined, unilocular hypodense lesion with internal calcifications and significant root resorption. A differential diagnosis included COC, adenomatoid odontogenic tumor, and calcifying epithelial odontogenic tumor. Histopathological analysis confirmed COC. Initial decompression was attempted, but due to non-compliance and lesion evolution, complete enucleation was performed. Postoperative follow-up at 6 and 18 months demonstrated significant bone regeneration, no recurrence, and preservation of pulpal vitality.</p> Conclusion <p>This case underscores the importance of a flexible surgical approach tailored to lesion evolution and patient compliance. CBCT played a critical role in diagnosis, treatment planning, and follow-up. Given the absence of standardized imaging protocols for COC, a structured follow-up strategy with CBCT and panoramic radiographs is recommended to monitor healing and detect recurrence.</p>

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Calcifying Odontogenic Cyst: A Case Report

  • 期刊论文

  • 出版模式：

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  • 发表日期：

    2026年2月5日

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  • Elen de Souza Tolentino,
  • Lukas Mendes de Abreu,
  • Mariel Ruivo Biancardi,
  • Fábio Vieira de Miranda,
  • Ana Regina Casaroto,
  • Izabel Regina Fischer Rubira Bullen,
  • Cassia Maria Fischer Rubira,
  • Camila Lopes Cardoso

摘要

Objective

To present a rare case of calcifying odontogenic cyst (COC), highlighting its clinical, radiographic, and histopathological characteristics, as well as the challenges in management and follow-up.

Case Report

A 20-year-old male patient presented with progressive tooth mobility in the mandibular anterior region. Cone beam computed tomography (CBCT) revealed a well-defined, unilocular hypodense lesion with internal calcifications and significant root resorption. A differential diagnosis included COC, adenomatoid odontogenic tumor, and calcifying epithelial odontogenic tumor. Histopathological analysis confirmed COC. Initial decompression was attempted, but due to non-compliance and lesion evolution, complete enucleation was performed. Postoperative follow-up at 6 and 18 months demonstrated significant bone regeneration, no recurrence, and preservation of pulpal vitality.

Conclusion

This case underscores the importance of a flexible surgical approach tailored to lesion evolution and patient compliance. CBCT played a critical role in diagnosis, treatment planning, and follow-up. Given the absence of standardized imaging protocols for COC, a structured follow-up strategy with CBCT and panoramic radiographs is recommended to monitor healing and detect recurrence.