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Introduction <p>As the incidence of oral cancer rises, treatment protocols are evolving alongside advancements in technology and expertise. The shift is driven by the goals of early detection and intervention, which aim to provide a better quality of life (QoL) for cancer survivors.</p> Aim and Objectives <p>To compare the QoL of patients treated with EBR and DR. Additionally, various other parameters such as recurrence, post-operative complications, and overall survival (OS) were considered.</p> Material and Methods <p>In this prospective comparative study, total twenty patients (ten in EBR and ten in DR group) who were affected by OSCC involving primarily the mandibular alveolus, tongue, buccal mucosa and floor of the mouth only, who underwent resection of the primary tumor and neck dissection during the same surgical session were considered. Follow up at every 1st week, 1st month, 3rd month and 6th month post-operatively was done and the included parameters were compared (IBM SPSS).</p> Results <p>Subsite mismatch (mandible vs. tongue) posed a confounding factor. At 6 months, DR patients had significantly better QoL in domains such as chewing, appearance, speech, and anxiety (p &lt; 0.05). EBR showed a trend toward better local control and survival outcomes, though not statistically significant.</p> Conclusion <p>Despite oncological adequacy, EBR compromises early QoL, especially in swallowing-related functions, due to subsite and surgical extent. Subsite heterogeneity must be considered when interpreting results.</p>

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Comparative Evaluation of En Bloc vs Discontinuous Surgical Resection in the Management of Oral Cancer

  • 期刊论文

  • 发表日期：

    2025年12月13日

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  • Isha Maheshwari,
  • Prajesh Dubey,
  • Apoorva Mowar,
  • Sooraj S. Pillai

摘要

Introduction

As the incidence of oral cancer rises, treatment protocols are evolving alongside advancements in technology and expertise. The shift is driven by the goals of early detection and intervention, which aim to provide a better quality of life (QoL) for cancer survivors.

Aim and Objectives

To compare the QoL of patients treated with EBR and DR. Additionally, various other parameters such as recurrence, post-operative complications, and overall survival (OS) were considered.

Material and Methods

In this prospective comparative study, total twenty patients (ten in EBR and ten in DR group) who were affected by OSCC involving primarily the mandibular alveolus, tongue, buccal mucosa and floor of the mouth only, who underwent resection of the primary tumor and neck dissection during the same surgical session were considered. Follow up at every 1st week, 1st month, 3rd month and 6th month post-operatively was done and the included parameters were compared (IBM SPSS).

Results

Subsite mismatch (mandible vs. tongue) posed a confounding factor. At 6 months, DR patients had significantly better QoL in domains such as chewing, appearance, speech, and anxiety (p < 0.05). EBR showed a trend toward better local control and survival outcomes, though not statistically significant.

Conclusion

Despite oncological adequacy, EBR compromises early QoL, especially in swallowing-related functions, due to subsite and surgical extent. Subsite heterogeneity must be considered when interpreting results.