Exploring the Impact of Only 20-Second Ultraviolet Irradiation on Stability of Titanium Dental Implants: A Prospective Randomized Controlled Trial
摘要
The success of dental implants is closely linked to the quality of osseointegration. Titanium implants undergo a time-dependent degradation in their bioactivity known as “implant aging,” largely due to surface accumulation of carbon-based contaminants, which reduces their osseointegration potential. Photofunctionalization, a process of ultraviolet (UV) irradiation has been proposed to reverse this aging effect. This study aimed to assess the impact of a novel, only 20-second UV exposure protocol on implant stability.
Materials and MethodsAn in vitro surface analysis using Scanning Electron Microscopy (SEM) and X-ray Photoelectron Spectroscopy (XPS) was conducted on two types of implants before and after 20 s of UV treatment. In the in vivo component, a prospective randomized controlled trial was then conducted with 22 implant sites (11 per group) in partially edentulous patients, with each implant representing a unique site per patient. Group A received photofunctionalized implants; Group B received untreated implants. Implant stability was assessed using resonance frequency analysis at placement (primary stability) and after three months (secondary stability). The Osseointegration Speed Index (OSI) was calculated as the monthly increase in the Implant Stability Quotient (ISQ). Statistical comparisons were made using the Mann-Whitney U test.
ResultsSEM revealed no change in surface morphology post-treatment, while XPS showed a reduction in surface carbon to 6%. There was no significant difference in primary stability (p = 0.622). However, secondary stability (p = 0.003) and OSI (p = 0.0002) were significantly higher in the photofunctionalized group.
ConclusionPhotofunctionalization using a 20-second UV exposure significantly enhanced implant stability over time, potentially allowing for earlier loading. While the study’s small sample size limits broad generalizability, findings support the feasibility of 20-seconds photofunctionalization. The study was not registered in a clinical trials registry, which may impact transparency.