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Aim <p>This study was conducted to evaluate the efficacy of amniotic membrane as an alternative for grafting oral soft tissue defects.</p> Material &amp; methods <p>20 patients with superficial intraoral soft tissue epithelial lesions were selected from the IPD &amp;OPD. In selected patients the lesion was excised and was covered with amniocare membrane and sutured with the surrounding tissues followed by dressing.</p> Results <p>Excision of the lesions &amp; coverage with amniotic membrane was successfully carried out without any discomfort. The membrane was found to be acceptable to handle as an intraoral graft material. Reduction in pain &amp; swelling was observed post-operatively after 1 week &amp; month. In 90% of the patients epithelization was good. Wound contracture was absent in 80% of the patients where as in 20% only slight contracture was present. Overall healing was proved to be good &amp; faster using amniotic membrane.</p> Conclusion <p>This study showed the clinical usefulness of human AM as a biological graft material when used intraorally. The results suggested that human AM is biologically acceptable graft to oral wounds and could be a suitable clinical alternative for repair of the oral defects.</p>

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Evaluation of Efficacy of Amniotic Membrane as an Alternative for Grafting Oral Soft Tissue Defects—in Vivo Study

  • 期刊论文

  • 发表日期：

    2025年9月29日

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  • Priyal Lathi,
  • Vikas Kunwar Singh,
  • Ruchika Tiwari,
  • Hetvi Saxena,
  • Ayush Garg

摘要

Aim

This study was conducted to evaluate the efficacy of amniotic membrane as an alternative for grafting oral soft tissue defects.

Material & methods

20 patients with superficial intraoral soft tissue epithelial lesions were selected from the IPD &OPD. In selected patients the lesion was excised and was covered with amniocare membrane and sutured with the surrounding tissues followed by dressing.

Results

Excision of the lesions & coverage with amniotic membrane was successfully carried out without any discomfort. The membrane was found to be acceptable to handle as an intraoral graft material. Reduction in pain & swelling was observed post-operatively after 1 week & month. In 90% of the patients epithelization was good. Wound contracture was absent in 80% of the patients where as in 20% only slight contracture was present. Overall healing was proved to be good & faster using amniotic membrane.

Conclusion

This study showed the clinical usefulness of human AM as a biological graft material when used intraorally. The results suggested that human AM is biologically acceptable graft to oral wounds and could be a suitable clinical alternative for repair of the oral defects.