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Background <p>Present study has compared local anaesthetic efficacy of two agents, 5% tramadol with adrenaline 1:80,000 and 2% lignocaine with adrenaline 1:80,000 for bilateral maxillary premolar extraction under supra-periosteal injection.</p> Materials and Methods <p>This prospective, split-mouth, double-blinded, randomised, clinical study was conducted on 69 patients requiring extraction of maxillary premolars bilaterally for orthodontic reasons. The study group received 5% tramadol hydrochloride, and the control group received 2% lignocaine hydrochloride. Parameters evaluated were pain on injection, onset and duration of anaesthesia, and post-extraction analgesia.</p> Results <p>Current study observed longer duration of anaesthesia for lignocaine than that of tramadol, <i>p</i> &lt; 0.001. Lesser perception of post-extraction pain and longer duration of analgesia was observed on tramadol side compared to lignocaine, <i>p</i> = 0.001. Consumption of analgesic tablets was more in lignocaine group, <i>p</i> = 0.022.</p> Conclusion <p>Tramadol can be safely employed as an alternative to conventional local anaesthetic agents through supra-periosteal injection due to its dual local anaesthetic and analgesic action.</p>

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Does Tramadol Match Lignocaine for Maxillary Tooth Extraction Under Supra-Periosteal Injection?—A Prospective Clinical Study

  • 期刊论文

  • 发表日期：

    2025年9月24日

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  • Shital Patel,
  • Rajan Savani,
  • Zenish Bhatti,
  • Taher Rupawala,
  • Shyam Chauhan,
  • Yashasvi Chavda

摘要

Background

Present study has compared local anaesthetic efficacy of two agents, 5% tramadol with adrenaline 1:80,000 and 2% lignocaine with adrenaline 1:80,000 for bilateral maxillary premolar extraction under supra-periosteal injection.

Materials and Methods

This prospective, split-mouth, double-blinded, randomised, clinical study was conducted on 69 patients requiring extraction of maxillary premolars bilaterally for orthodontic reasons. The study group received 5% tramadol hydrochloride, and the control group received 2% lignocaine hydrochloride. Parameters evaluated were pain on injection, onset and duration of anaesthesia, and post-extraction analgesia.

Results

Current study observed longer duration of anaesthesia for lignocaine than that of tramadol, p < 0.001. Lesser perception of post-extraction pain and longer duration of analgesia was observed on tramadol side compared to lignocaine, p = 0.001. Consumption of analgesic tablets was more in lignocaine group, p = 0.022.

Conclusion

Tramadol can be safely employed as an alternative to conventional local anaesthetic agents through supra-periosteal injection due to its dual local anaesthetic and analgesic action.