Introduction <p>The cancer landscape in India is defined by a heavy burden of disease, stark mortality disparities, and significant gaps in survivorship care. Despite lower cancer incidence rates compared with high-income countries, the region experiences disproportionately high mortality rates due to late diagnoses, limited healthcare infrastructure, and widespread inequities in access to treatment.</p> Purpose <p>Distinctive risk factors, such as tobacco use and infection-related malignancies, further intensify the burden. Survivorship care remains underdeveloped, with cultural stigmas and systemic barriers compounding the challenges faced by cancer survivors.</p> Result <p>This review synthesizes the state of knowledge on cancer incidence, mortality, and survivorship care across India and other parts of Asia, presenting insights from epidemiological studies, projections, and qualitative data.</p> Conclusion <p>Addressing these challenges will require an integrated, multidisciplinary approach that strengthens prevention, reduces morbidity and mortality, and improves survivorship outcomes tailored to regional realities.</p>