Cemento-Ossifying Fibroma: A Diagnostic Revisit

Cemento-ossifying fibroma (COF) is one of the rare forms of benign fibro-osseous lesions. Establishing a differential diagnosis for COF could be an arduous task considering its resemblances with other fibro-osseous lesions like the Paget’s disease and fibrous dysplasia with regards to their clinical and radiographic presentation. Thus, the need for precise details pertaining to this entity. We report a case of mandibular COF in a young individual whose clinical and radiographic presentation was similar to any other routinely encountered odontogenic cyst or tumour. This edifies us that the microscopic examination undoubtedly remains the key modality for the final diagnosis of a COF where the clinical and radiographic presentation does not facilitate a clear-cut precise diagnosis. Thus, necessitating the need for a correlation between the clinical, radiological, and histological presentation to establish a definitive diagnosis.