Pyoderma Gangrenosum with Oral Involvement and Multidisciplinary Management

期刊论文
发表日期：

2024年6月11日

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Héric de Souza Camargo,
Carolina da Silva Nunes,
Claudia Maria Navarro,
Elaine Maria Sgavioli Massucato,
Marisa Aparecida Cabrini Gabrielli,
Valfrido Antonio Pereira Filho,
Andreia Bufalino

摘要

Introduction

Pyoderma gangrenosum (PG) is a rare neutrophilic dermatosis often associated with inflammatory bowel disease.

Case report

We present a case of PG affecting the oral mucosa in a 31-year-old female with ulcerative colitis, necessitating total colectomy due to aggressive lesion progression. Despite initial adalimumab treatment, the lesions persisted, prompting a multidisciplinary approach. Following surgical intervention, including total colectomy and microvascularized graft with a forearm flap, the patient remained recurrence-free during a seven-year follow-up.

Conclusion

This case underscores the complexity of PG and highlights the efficacy of a comprehensive therapeutic approach, emphasizing the importance of individualized management strategies in severe cases.